Two people have been seriously injured after a motorcycle collided with a car in Perth’s south-eastern suburbs on Friday night.

WA Police said a yellow and black Suzuki motorcycle and a gold Toyota Camry crashed just before 9pm at the intersection of Eudoria and Walter streets in Gosnells.

Two 20-year-old male riders of the motorcycle were thrown several metres into the air before landing against a nearby fence.

Both were seriously injured. St John WA transported both riders to Royal Perth Hospital under priority one conditions, where they remain in a stable condition with non life threatening injuries.

The 20-year-old male driver of the Camry was uninjured and remained at the scene.

The front of his car was severely damaged, with debris left scattered across the scene.

Inquiries are ongoing, with police asking anyone with information to contact Crime Stoppers on 1800 333 000.

Police urged all motorists to take care on the road.